If you’re thinking about moving to Upstate South Carolina, you’re in for a treat. This region offers a little bit of everything — vibrant cities, charming small towns, and breathtaking mountain views — all within a short drive of each other.

The Upstate, sometimes called the Greenville-Spartanburg-Anderson region, stretches across the northwestern corner of South Carolina and is home to some of the state’s fastest-growing and most livable communities.

So, where should you live in Upstate SC? Let’s explore the area’s most popular cities and towns — what makes each one special, who it’s perfect for, and how the housing market looks today.

Greenville: Heart of the Upstate

The largest city in the region, Greenville blends Southern charm with modern energy. Its revitalized downtown, lined with restaurants, galleries, and green space, consistently ranks among the best in the South.

Greenville is known for its walkable city center, diverse food scene, and young, professional population. The Swamp Rabbit Trail and Paris Mountain State Park offer outdoor escapes just minutes from Main Street.

Median Home Price: $425,000

Why people love it: Greenville offers big-city amenities with a small-city feel — perfect for professionals, creatives, and retirees who want an active lifestyle.

Travelers Rest. Outdoor Paradise with a Creative Soul

Locals call it “TR,” and it’s one of the most picturesque towns in the Upstate. Tucked against the Blue Ridge Mountains, Travelers Rest is famous for its Southern hospitality, biking culture, and artistic community.

The Swamp Rabbit Trail runs right through downtown, connecting cyclists and visitors to Greenville. You’ll find boutique shops, local breweries, and cozy restaurants — all with mountain views.

Median Home Price: $602,485

Why people love it: It’s ideal for outdoor lovers, artists, and retirees who want a laid-back lifestyle surrounded by nature and creativity.

Greer, SC. Growth, Opportunity & Global Connections

Nestled between Greenville and Spartanburg, Greer has become a major hub for innovation. It’s home to BMW Manufacturing and more than 35 international companies, creating strong job growth and new neighborhoods.

Greer’s historic downtown has been revitalized with restaurants, shopping, and a small-town atmosphere. The Blue Ridge backdrop adds natural beauty to the area’s booming economy.

Median Home Price: $465,000

Why people love it: Perfect for career-focused professionals and families who want newer homes, short commutes, and a thriving local economy.

Simpsonville, SC. Southern Charm Meets Modern Convenience

Just 20 minutes from downtown Greenville, Simpsonville offers a family-friendly feel with easy city access. The city’s slogan, “Simply Home,” captures its warm, welcoming atmosphere.

Simpsonville features beautiful parks, great schools, and a walkable downtown filled with restaurants, shops, and community events. The area’s strong economy and high median income reflect its growing popularity.

Median Home Price: $439,000

Why people love it: Simpsonville is one of Greenville County’s best suburbs, ideal for families and retirees seeking comfort, community, and convenience.

Mauldin, SC. Affordable, Connected, and Growing Fast

Consistently ranked among the most affordable places to live in South Carolina, Mauldin offers easy access to Greenville and a strong sense of community.

It’s home to BridgeWay Station, an exciting mixed-use development filled with shops and restaurants, and the new Mauldin Gateway Bridge, which will soon connect to the Swamp Rabbit Trail.

Median Home Price: $365,000

Why people love it: Mauldin is great for young families and professionals who want affordability, modern amenities, and quick commutes to Greenville.

Taylors, SC. Creativity Between Two Cities

Located between Greenville and Greer, Taylors is a fast-growing community with deep roots and a creative heartbeat.

The revitalized Taylors Mill has become a local landmark — filled with art studios, breweries, small businesses, and community events. Thousands of homes line Wade Hampton Boulevard, offering plenty of options for new buyers.

Median Home Price: $425,000

Why people love it: Taylors combines suburban comfort with creative flair, making it ideal for first-time buyers, entrepreneurs, and families.

Easley & Powdersville, SC. Small-Town Feel, Big Convenience

Easley and Powdersville are neighboring communities known for good schools, affordability, and a relaxed lifestyle. Easley has a lively downtown with local shops and family events, while Powdersville offers newer neighborhoods and a strong suburban feel.

Many residents work remotely or commute to Greenville, balancing small-town life with city convenience.

Median Home Price (Easley): $374,900

Why people love it: Great for families and remote workers who want value, space, and a strong community atmosphere.

Anderson, SC. The Electric City

Located along I-85 between Charlotte and Atlanta, Anderson offers small-town charm with big-city access. Known as “The Electric City,” it was one of the first in the Southeast to have electricity and continues to attract growth through major employers like Michelin, Arthrex, and Bosch.

Anderson is diverse, welcoming, and full of local pride — from its historic downtown to neighborhoods near Lake Hartwell.

Median Home Price: $340,000

Why people love it: Affordable homes, steady jobs, and a friendly atmosphere make Anderson perfect for first-time buyers and families.

Spartanburg, SC. The Hub City

Spartanburg is a college town with a creative streak. Home to seven colleges and universities, it’s full of energy, arts, and innovation. The city’s revitalized downtown now buzzes with music, restaurants, and public art.

Manufacturing and tech industries are growing fast here, keeping housing affordable while the local culture thrives.

Median Home Price: $297,290

Why people love it: Spartanburg offers affordable living, cultural energy, and college-town vibes — ideal for young professionals and first-time homebuyers.

Pickens, SC – Mountain Views & Peaceful Living

Tucked into the foothills of the Blue Ridge Mountains, Pickens is the perfect escape for nature lovers. Residents enjoy hiking, fishing, and mountain views every day, with Table Rock State Park just minutes away.

Downtown Pickens is small but charming, filled with local shops, restaurants, and community events.

Why people love it: A quiet, affordable lifestyle surrounded by mountain scenery and outdoor adventure.

Laurens, SC. Historic Charm and Southern Hospitality

With its beautiful Downtown Square, Laurens feels like a step back in time — in the best way. The city blends history, hospitality, and hometown pride, offering parks, good schools, and family-friendly living within a short drive of Greenville.

Median Home Price: $216,300

Why people love it: A peaceful, affordable community where neighbors still know each other and small-town values shine.

Fountain Inn, SC. Friendly, Affordable, and Growing

Located near Simpsonville and Mauldin, Fountain Inn offers quiet neighborhoods, a charming downtown, and easy access to I-385. It’s one of Greenville County’s fastest-growing suburbs and a favorite for first-time homebuyers.

Median Home Price: $329,000

Why people love it: Fountain Inn delivers affordable housing and small-town friendliness just minutes from Greenville.

FAQs About Living in Upstate South Carolina

Where is the best place to live in Upstate SC?

The best place depends on your lifestyle:

• Urban + amenities: Greenville or Greer
  
• Outdoor lifestyle: Travelers Rest or Pickens
  
• Family living: Simpsonville, Mauldin, or Easley
  
• Affordable options: Spartanburg or Anderson
  
  

What are the Upstate areas of South Carolina?

The Upstate includes Greenville, Spartanburg, and Anderson Counties, plus surrounding towns like Greer, Mauldin, Simpsonville, Easley, Travelers Rest, Taylors, Pickens, and Laurens.

What is the nicest area to live in South Carolina?

For mountain views and culture, Greenville and Travelers Rest top the list. Along the coast, Charleston and Beaufort often earn top honors — but the Upstate wins for affordability, convenience, and access to both mountains and beaches.

What is the safest city to live in in South Carolina?

Safety varies by neighborhood, but Mauldin, Simpsonville, and Travelers Rest consistently rank among the safest Upstate communities. Always check current local crime statistics before moving.

Final Thoughts

Whether you’re drawn to Greenville’s city energy, Travelers Rest’s mountain trails, or Anderson’s affordability, Upstate South Carolina has a community that fits your lifestyle.

From mountain towns to modern suburbs, the region combines Southern hospitality, strong job growth, and scenic beauty — making it one of the best places to live in the Southeast.

👉 Ready to find your perfect Upstate home?
Contact Hamilton & Co. for a personalized market analysis, local guidance, and the latest Altos Research data for your favorite neighborhoods.